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Thymic Development and Selection of T Lymphocytes

Thymic Development and Selection of T Lymphocytes - Current Topics in Microbiology and Immunology

2014

Hardback (19 Nov 2013)

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Publisher's Synopsis

The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.

Book information

ISBN: 9783642402517
Publisher: Springer Berlin Heidelberg
Imprint: Springer
Pub date:
Edition: 2014
DEWEY: 571.966
DEWEY edition: 23
Language: English
Number of pages: 132
Weight: 3376g
Height: 235mm
Width: 155mm
Spine width: 16mm