Publisher's Synopsis
This book brings together recent advances in our understanding of the regulation of the phospholipase C pathway. The authors are from leading research laboratories who not only give an overview of this rapidly evolving field, but also outline current thinking and working models. The topics discussed encompass a wide range of disciplines within cell biology and reflect the multiple sites of regulation of this pathway from receptor phosphorylation to regulation of the intracellular calcium channels (IP3 receptor). This book is the first to bring together these topics, with the aim to increase appreciation and conceptual understanding of the phospholipase C signalling process.