Publisher's Synopsis
The symposium on "The Pharmacology of Cell Differentiation", upon which this text is based, has been structured to begin with an exploration, first of general, then more specific mechanisms implicated in the inter- and intra-cellular systems exploited by cells for the transduction of growth and developmental signals; then to examine the intracellular machinery for cell growth regulation, the gene-expression control mechanisms identified in transformed and normal cells; and finally to move to selected examples illustrating the exploitation of these findings for the induction of developmental changes in real cancers. This is not a review of established successes in cancer therapy; rather it is a progress report on work on-going at one of the frontiers of contemporary pharmacology.
