Publisher's Synopsis
This series of essays deals with the structure and function of the normal blood-brain barrier, examining how barrier functions alter in disease, and how pathological changes may be measured. Topics covered include the role of endothelial cells and glia in barrier breakdown, the barrier in chronic relapsing and in acute experimental allergic encephalomyelitis, and the effects of methylmercury on glucose transport. Additional chapters consider how plasma solutes may or may not cross the blood-brain barrier and investigate the immunological significance of leucocyte-endothelial interactions for such diseases as multiple sclerosis.
