Publisher's Synopsis
This manual has now been completely revised, expanded, and updated to cover the most advanced instrumentation and techniques. The second edition's expanded coverage includes three separate chapters on peripheral blood culture, continuous cell lines, and prenatal diagnosis and culture and new chapters on solid tumours, fragile sites, and molecular cytogenetics. The manual provides a survey of techniques for visualization and analysis of human chromosome patterns in diagnosis and research.;More than 200 step-by-step protocols are presented at the most helpful points throughout the text. And the authors provide a variety of techniques so that the experienced technologist will have a choice but the novice will not be overwhelmed. Other useful features include almost 200 illustrations (14 in full colour), an index, and a new design that aims to make protocols and text easier to follow.