Publisher's Synopsis
A Complete Guide to Preclinical Drug Evaluation
Are you a pharmacy student, pharmacologist, or biomedical researcher looking for a complete and practical reference on pharmacological screening?
Textbook of Pharmacological Screening: Experimental Models, CPCSEA & OECD Guidelines, and Drug Evaluation Methods in Preclinical Research is your comprehensive resource to master the principles and applications of drug testing in preclinical settings.
Designed as per the B.Pharm syllabus (PS608: Screening Methods in Pharmacology - Open Elective II), this book offers clear explanations and well-structured chapters on the care, handling, breeding, and ethical use of laboratory animals.
Key Features:
Covers pharmacological screening methods for CNS, cardiovascular, metabolic, gastrointestinal, and inflammatory disorders
Step-by-step procedures for models like tail-flick test, carrageenan-induced paw edema, yeast-induced pyrexia, and many more
Aligned with CPCSEA, OECD, ICH, and FDA regulatory frameworks
Discusses acute, sub-chronic, chronic, reproductive, and teratogenic toxicity studies
Includes alternatives to animal experimentation: in vitro, ex vivo, in silico, and zebrafish models
Ideal for B.Pharm, M.Pharm, and biomedical science students
Whether you are preparing for lab practicals, university exams, or early-stage drug discovery research, this book equips you with the scientific, ethical, and regulatory foundation needed to excel in preclinical pharmacology.
