Publisher's Synopsis
Animal models of some autoimmune diseases have indicated restricted T-cell receptor use and have suggested therapies based on those data. Patients with naturally occurring diseases have not shown a consistent picture of receptor utilisation. This volume discusses the spectrum of T-cell receptor use in human disease, the relationship between the human and animal findings, and the biological and therapeutic implications of the former.;This text contains papers presented at a conference sponsored by the New York Academy of Sciences and the Arthritis Foundation on 17th-20th April, 1994, in San Diego, California, USA.;There are 31 papers.