Publisher's Synopsis
This book provides a practical, mechanism-oriented coverage of beneficial chemotherapeutic drug interactions in the clinic and in experimental model systems. Anticancer, antimicrobial, and antiviral systems are included, as well as methodology for characterization and quantitation of synergism and antagonism. An overview chapter integrates diverse aspects of the field, and individual chapters give unique and timely treatment of specific topics. This book will be a useful tool for those interested in drug combination design because it reviews mechanistic information on both combinations of experimental agents and drugs used clinically. It is intended for students, clinicians, and researchers in medicine, pharmacology, chemistry, and biochemistry.
