Publisher's Synopsis
This book contains contributions by world renowned researchers on recent progress on serotonin research. In central nervous system, papers deal with 5-HT receptors, animal models of anxiety, feeding, cognition, migraine, relationship of 5-HT system with Alzheimer disease, development of antipsychotic drugs, and involvement of platelets in depression. In the periphery the roles of 5-HT and effects of antagonists of 5-HT receptors in the circulation are presented. Some main features of the book include: recent progress on the regulation of 5-HTergic transmission and its implications for the treatment of patients with emotional disorders; new developments on the relationships of 5-HT system with feeding, migraine, cognition, anxiety and etiology of Alzheimer's disease; and roles of 5-HT and its antagonists in the maintenance of the integrity of blood flow in health and disease.