Publisher's Synopsis
This book endeavours to present an overview of the most important developments in prostacyclin research over recent years. The first part of the book deals with the three most relevant new areas of prostacyclin research: 1) analysis of novel mechanism(s) of action in "traditional" target cells (vascular smooth muscle and platelets); 2) study of the effect of prostacyclin on novel targets (e.g. endothelium), and 3) examination and potential therapeutic use of the unique cytoprotective and antiatherosclerotic properties of prostacyclin. Based on the progress made in these basic research areas the second part of the book evaluates the potential new therapeutic applications of stable prostacyclin analogues in atherosclerosis, congestive heart failure, ischemic heart disease, diabetes, pregnancy and tumor metastasis.;The information summarized in this book provides an excellent reference for basic scientists and clinicians alike who are actively involved or interested in prostacyclin research and its practical application.
