Publisher's Synopsis
How do you translate bench chemistry into 10-100 litre pilot plant scale? Drawing on the experience of its contributors, this is an insight into how methods, procedures and techniques can be optimized. It addresses topics including the choice of phase-transfer catalyst, safe scale-up of both Grignard and organolithium reactions, and on-line techniques for examining crystallisation. Collaborative industry/academia projects are discussed, along with other procedures that have a practical application in industry.
