Publisher's Synopsis
The problem of producing drugs with a high level of stability is the subject of this volume, which is part of a series designed to reflect new advances in pharmaceutical chemical discoveries. It contains a series of essays by international researchers who present a range of topical issues.;Starting with a review of the value of cyclodextrins in pharmaceutical technology, the text shows how the stability of this group of compounds may be increased by the inclusion of other molecular compounds, thus increasing resistance towards heat and lowering thermal resistance. Transitions are observed in differential thermal analysis and electrical conductivity, and the potential of these methods to produce different drug forms during freeze drying is analyzed. The use of colloidal and porous silicas as carriers in solid, semi-solid and liquid dose forms is also examined.;There is a review of silica gel production systems, which are of interest to the ceramics industry for high purity silicate glass production as well as the pharmaceutical chemist, due to their low temperature processing capacity. The advantages of soft paraffin - widely used in pharmaceutical and cosmetic formulation - are described, as well as the advantages, in terms of selectivity, time saving and economy, of using short and ultra-short HPLC columns for the analysis of compounds.
