Publisher's Synopsis
Excerpt from On the Production and Suppression of Muscular Twitchings and Hypersensitiveness of the Skin by Electrolytes
To test this idea further, Mr. W. E. Garrey and I undertook, in 1899, a series of experiments, not yet published, on the behavior of muscles in solutions of sodium salts whose anions precipitate calcium. The muscle itself contains calcium Salts, and we considered it likely that these calcium salts might help in preventing contractions. We therefore thought that by putting the muscle into solutions of sodium salts, which, by entering the muscle, precipitate the calcium contained In it, we might produce still more powerful rhythmical contractions than In a pure sodium chloride solution. This was found to be true. In Solutions Of sodium ?uoride, -oxalate, -carbonate, -phos phate, etc., of the proper concentration (1 gram-molecule in 8 liters of the solution), we Obtained similar, but more powerful, rhythmical contractions than in sodium.
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