Publisher's Synopsis
This text on the silyl method for the synthesis of nucleosides originated as a modification of the classical method and uncovers one of the basic methods for the preparation of nucleosides and their analogues.;The synthesis of nucleosides is an essential feature in research programmes concerned with anti-cancer chemistry and in other areas of pharmaceutical importance. The book covers theoretical aspects and the applicability of the silyl method for synthesizing nucleosides. A systematic approach to silylation of the diverse heterocyclic bases is provided, together with classification of the experimental data. All the methods for nucleoside synthesis are carefully analyzed, and clear, succinct tables summarize the experimental results.
