Publisher's Synopsis
Excerpt from National Institute of Child Health and Human Development, Annual Report of Intramural Research: October 1, 1984 Through September 30, 1985
By immunoprecipitating the antigen receptor with a monoc1ona1 antibody directed against the unique binding site of the receptor, we have identified a specific set of proteins which are non- cova1ent1y associated with the c1onotypic a and 8 chains, that a1one previous1y' defined the receptor. Four unique proteins, termed v, 6, c, 8 C comprise this comp1ex. They are a11 expressed on the surface of the T ce11 and are most 1ike1y a11 transmembrane proteins and one is a homodimer. Thus the minimum comp1ex that defines the T cc11 antigen receptor contains seven chains inc1uding the a - B dimer that recognizes specific antigen.
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