Publisher's Synopsis
The existence of oncogenes has transformed the understanding of cancer and supported new approaches to therapy. The purpose of this volume is to review critically the potential utility of oncogenes and tumour suppressor genes as targets for novel forms of rational anti-cancer therapy. After examining the basic biology of selected growth factor receptor molecules and suppressor molecules in human cancers, this book discusses in depth various ways in which knowledge of these systems can be used in clinical practice.;"Mutant Oncogenes" includes contributions from internationally renowned clinicans and cancer scientists who have provided the first book to review this exciting approach to cancer therapy.