Publisher's Synopsis
Multicomponent reactions, which can be regarded as masterpieces of synthetic efficiency and reaction design, have been around since the very early days of organic chemistry. Today, together with new concepts in chemical reactivity that range from radical reactions through organometallic chemistry and catalysis to organo- and enzyme-catalyzed reactions, unprecedented sequences are being invented. This volume covers multicomponent reactions involving an a,á-unsaturated carbonyl compound as an electrophilic component. Reactions involving cycloaddition as a key step are also discussed, as well as boron-, silicon-, and free-radical-mediated multicomponent reactions. Finally, both stoichiometric and catalytic metal-mediated multicomponent reactions are reviewed.