Publisher's Synopsis
Multicomponent reactions, which can be regarded as masterpieces of synthetic efficiency and reaction design, have been around since the very early days of organic chemistry. Today, together with new concepts in chemical reactivity that range from radical reactions through organometallic chemistry and catalysis to organo- and enzyme-catalyzed reactions, unprecedented sequences are being invented. This volume covers multicomponent reactions involving a carbonyl compound as an electrophilic component. All of the major multicomponent name reactions fall into this classification, and included are reviews of the Biginelli reaction, the Hantzsch pyridine synthesis, the Strecker reaction, the Mannich reaction, the Petasis reaction, the Passerini reaction, and the Ugi reaction, among others.