Publisher's Synopsis
A molecular and cellular biological approach to human immuno-deficiency and autoimmunity. Coverage includes descriptions of the cytokines and cellular mediators necessary for integrated and well-regulated immune responses. The antigenic stimuli, histocompatibility variants, lymphocytic defects and effector cell abnormalities central to selected human hypersensitivity and autoimmune diseases are also covered, as are molecular strategies to novel therapies for immune diseases using monoclonal antibodies or receptor-specific immunotoxins.