Publisher's Synopsis
Molecular biology is reshaping how diseases are screened for, diagnosed, investigated and treated. Molecular biology is changing the way that medicine is practiced and yet, for many, the subject still seems difficult and impenetrable. Molecular Biology in Medicine provides a guide through the concepts, language and approaches of molecular biology and shows how it is applied to the practice of medicine. It introduces the basics of gene structure, gene expression and how genetic defects contribute to disease. Individual chapters show how molecular biology underpins our understanding of disease mechanisms and gives details of how this can be used to provide better healthcare, now and in the future. Molecular Biology in Medicine includes: Fundamentals of DNA, RNA and protein structure and function The regulation of gene activity How to analyse human genes and the principles of medical genetics Cancer Monogenic and polygenic disorders Microbial infections Haemophilia Disorders of the immune system Recombinant products for medical use Drug discovery and gene therapy Prenatal diagnosis and ethics A detailed glossary Clinical correlations stressing the clinical applications of the basic science Molecular Biology in Medicine will appeal to a diverse readership, from practicing physician or higher examination candidate, who wants to refresh their knowledge of molecular biology; to medical researchers who want to expand their knowledge beyond their ever–shrinking specialist subject; and to the medical and biomedical science student.