Publisher's Synopsis
This text introduces clinicians to the extraordinary power and importance of molecular biology in the research and treatment of cancer. It explains how new techniques involving the manipulation of genetic material in cells and organisms provide dramatic insight into how cell behaviour is subverted in common human cancers. The book shows how techniques of cell and molecular biology improve the understanding and effectiveness of radiation and drug actions, and leads to the development of gene therapy. Ultimately, techniques of molecular biology will help to identify the specific genetic and environmental factors predisposing to cancer, offering the means of cancer prevention. About half of the authors are scientists established in their fields.;The other half are practising oncologists applying the techniques of molecular biology to their own research. They have all been asked to provide a teaching document rather than a detailed review with emphasis on clear explanations and clinical relevance. A separate section is included which specifically describes the most common and important techniques in molecular biology. A glossary of terms and a comprehensive index are also provided. The book will be of value to all medical, radiation and surgical oncologists whether in practice, training or research. It will also be useful for university-based courses for specialists, particularly those who recognize the need to develop the interface between the clinic and the laboratory.
