Publisher's Synopsis
Renal production and the controlled excretion of ammonia play a pivotal role in the regulation of acid-base homeostasis. This volume, based on an international workshop, brings together the latest research findings on molecular aspects of ammoniagenesis. Sections dealing with enzyme and substrate metabolism; pathophysiology in renal ammonia metabolism; ammonia metabolism in the human kidney; ammonia production and transport along the nephron; extrarenal ammonia metabolism and the use of NMR in ammonia metabolism, as well as gene expression of glutaminase and its related enzymes.