Medicinal Implications in Cytochrome P-450 Catalyzed Biotransformations

This volume in the uniscience series "Frontiers in Biotransformation" contains six chapters which cover a broad range of topics, from recent data elaborated in basic research laboratories to their application in diagnosis and therapy. More than two decades of laborious investigations have passed since the discovery of the P-450 enzyme systems as being essential for the efficacy of drugs till the first selective applicaiton of P-450 inhibitors targeted on the treatment of malignant tumours and fungal diseases. But this is just the beginning of a development which will lead to new drugs with more selectivity and less side effects based on new principles in therapy.;The volume provides an abundance of interesting informaiton and stimulation and therefore is recommended to all bioscientists interested in that field.