Publisher's Synopsis
Fascinating new research results have shown that testicular germ cell neoplasia can be detected before it becomes invasive and that, at this preinvasive stage, the disease can also - in some cases - be cured without removing the testis. This was the message which came through at the international workshop which was the basis for this publication. This report covers a wide range of topics including the biology, epidemiology, screening, pathology, surgical management, radio- and chemotherapy of carcinoma in situ of the testis and invasive cancer. The contributors are American and European urologists, oncologists, pathologists and endocrinologists, all experts in their field, who give authoritative reviews of the latest findings on every aspect of testicular cancer. Advances in the research on the cytogenetics and pathogenesis of the disease are presented, and the effects of therapy on fertility and the endocrine function of the testis are described. New methods of predicting the outcome of the disease are discussed and the role of very aggressive therapy with bone marrow transplantation for very poor prognosis patients is analyzed.;A major topic at the conference was the risk of bilateral disease, which is an important feature of testicular cancer. In the course of the discussions, changing attitudes towards the importance of testicular biopsy emerged, and new guidelines for urological surgical practice were produced.
