Publisher's Synopsis
The book discusses the significance and value of isolated hyperthermic limb perfusion as clinical treatment. The effect of a combination of hyperthermia, chemotherapy and hyperoxygenation on solid tumors is described from the perspective of pathophysiology. The surgical and perfusion techniques are discussed based on the authors' clinical and experimental experience in more than 100 perfusions. The indications and contraindications are also reviewed. The methods presently used to measure the volume of leakage from the perfusion circulation are described from the viewpoint of nuclear medicine, and their advantages and disadvantages are discussed. One chapter is devoted to the clinical results after and the side effects and complications of limb perfusion in melanoma and sarcoma patients.
