Publisher's Synopsis
Interleukin-8 (IL-8) is a peptide with chemotactic and activating effects on neutrophils. It is recognized today as the prototype of a new class of chemotactic cytokines which are gaining increasing attention as tissue-derived inflammatory mediators. Four years after the identification of IL-8, this book presents an overview of the biochemical, molecular biological and pathophysiological properties of this new class of inflammatory proteins. Written by leading researchers, this collection of essays can not only be used as a reference source for those already active in the field, but also provides detailed information for newcomers interesed in chemotactic cytokines and their implication in inflammation and host defence.
