Publisher's Synopsis
This volume is devoted to the inositol phosphate-calcium signalling system, a cellular signalling system that plays a crucial role in diverse biological processes, influences the actions of drugs and hormones used to treat a wide variety of clinical disorders, and is implicated in the actions of growth factors and oncogene products. More than 30 of the world's investigators discuss concepts on the formation and metabolism of inositol phosphates, the functions of these molecules as second messengers regulating calcium signalling mechanisms and the role of the inositol phosphate-calcium signalling system in neuronal function, muscle contraction, cell secretion, metabolic regulation, and cell growth and differentiation. The contributors address many controversial questions regarding this complex signalling system.
