Publisher's Synopsis
This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting-edge science associated with them. Following the editors' 3 successful drug synthesis books, this provides expert analysis of the pros and cons of different synthetic routes and demystifies the process of modern drug discovery for practitioners and researchers.
- Summarizes for each drug: respective disease area, important properties and SAR (structure-activity relationship), and chemical synthesis routes / options
- Includes case studies in each chapter
- Illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines
- Explains the advantages of process synthesis versus the synthetic route for drug discovery
