Publisher's Synopsis
This book explores the area of techniques for obtaining protein/peptide sequence information. It aims to provide an up-to-date review of the methods available and discusses the limitations of the Edman degradation, introducing important techniques in mass spectrometry.;The values of a wide range of complementary techniques, including gas phase microsequencing, mass spectrometry and HPLC techniques, are covered from the viewpoint of the ways in which they can help in identifying modified peptides and NMR techniques.;The book employs an integrated approach, combining DNA sequencing with direct protein microsequencing, together with the ancillary techniques mentioned above.
