Publisher's Synopsis
It is generally agreed that primary hypertension is a multifactorial disorder where both genetic and environmemntal factors play an important role. In recent years it has become evident that hypertension is closely associated with a number of metabolic risk factors for cardiovascular disease. Insulin resistance and hyperinsulinemia seem to play a key role in the development of these risk factors. An increasing body of evidence also suggests that insulin may be directly involved in the pathogenesis of hypertension. Thus investigators representing different disciplines and approaches have critically reviewed the molecular and clinical evidence for the role of insulin in the pathogenesis of hypertension in this volume. Also suggested are possible interactions of insulin with genetic and environmental factors. This book succeeds in generating new approaches and defining areas needing further exploration, as well as contributing to the better understanding of the subject as a whole.
