Publisher's Synopsis
This text on basophils and mast cells discusses such topics as: their ultrastructural and phenotypic characteristics; fundamental biochemical aspects, including the high-affinity receptor for IgE; production of cytokines in vitro and in vivo; activation under cytokine influence; and interaction with the neuroimmune system and other inflammatory cells.;The chapters have all been written by leading scientists and clinical investigators, with the focus on the research they themselves are actively engaged in. A companion volume is available which covers the clinical aspects of human basophils and mast cells.