Publisher's Synopsis
"it is a pleasure just to read this handsome and carefully produced work" Angewandte Chemie 2002
"...the Handbook of Metalloproteins is highly recommended as a resource for bioinorganic chemistry. It will have lasting value for researchers in the field..." The Alchemist – Chemweb
In recent years, the analysis and classification of metalloproteins at the interface between chemistry and biology has accelerated. Many developments and initiatives have taken place and this two–volume handbook provides a comprehensive, yet focussed, collection of 105 major metalloproteins. Content is presented in both a large format and full colour and covers the most relevant transition metals such as Iron, Nickel, Copper, Cobalt, Molybdenum, Manganese Tungsten and Vanadium.
This is the first Handbook of Metalloproteins ever published and is comprised of articles written by renowned experts in the field. It draws together contributions from over two hundred internationally renowned researchers that include: Douglas Rees and Charles Stout as well as Nobel Prize winner Robert Huber.
Each contribution is presented in a similar format and shows a ribbon plot of the overall 3D Structure on their first page, a representation of the metal active site and numerous other figures and tables underpinning the remarks. Comparative information is provided on different proteins and every entry has been extensively referenced to current literature.
∗ First comprehensive handbook to cover the major metalloproteins
∗ Presents structural and functional data in an organised manner
∗ Incorporates full–colour representation of molecular structures throughout
∗ Unifies information from molecular biology, enzymology, spectroscopy, biochemistry, chemistry, biophysics, macromolecular crystallography and structural biology
∗ Includes comprehensive sections that cover: Functional Class, Occurrence, Amino Acid Sequence Information, Protein Production, Purification and Molecular Characterisation, Metal Content and Cofactors, Activity Test, Spectroscopy, 3D Structure, Functional Aspects.
