Publisher's Synopsis
First published in 1976, the Handbook of Basic Pharmacokinetics…Including Clinical Applications is known for being a user-friendly consolidation of pharmacokinetic principles and techniques for practitioners, researchers, and students that merits a place in any personal or college library. In this seventh edition, 10 chapters have been substantially revised to address recent developments and incorporate new information, illustrations, and equations and up-to-date literature citations. The appendix has been expanded to include parameters for some 150 additional drugs, bringing the total to more than 790.
Key Features:
- Chapters on the following topics have been updated: Absorption/Transport Mechanisms, Physicochemical and Biological Factors Affecting in vivo Performance of Drugs, Drug Biotransformation, Excretion and Clearance of Drugs, Pediatric Pharmacokinetics, First-Dose Size in Man, Correlation of Clinical Response with Drug Disposition, Bioavailability and Bioequivalence, Extracorporeal Methods of Drug Removal, and Pharmacogenetics and Pharmacogenomics.
- More than 100 pharmacokinetic terms are defined in Chapter 1.
- Pharmacokinetic data compiled from the literature on nearly 800 drugs-150 new to this edition-are presented in the tabular appendix.
