Publisher's Synopsis
The bone marrow trephine biopsy is a relatively recent investigative tool dating from 1958. It is of growing importance for the diagnosis of a broad range of hematological malignancies, and its relative efficacy, as compared to imprints and smears, has been proven. In this special issue of 'Pathobiology', distinguished international experts review a selection of the most exciting current topics in bone marrow pathology, including the morphological diagnosis and classification of the chronic myeloproliferative diseases, acute myeloid leukemia, malignant lymphoma and mastocytosis. The possibilities and limitations of bone marrow biopsies in diagnosis and prognosis are discussed in detail. Both hematologists and histopathologists should find valuable information for their day-to-day practice.
