Publisher's Synopsis
This special topic issue presents a selection of papers from the International EMT meeting held in Melbourne, October, 2015. The recent TEMTIA meetings have identified the emerging trends of big data and complex systems biology. A specific focus is on the positive impact that new methods of systems analysis can have on identifying novel regulators of EMT. There is also emphasis on the utility of mathematical models for assessing potential effects of EMT on the emergent behavior of tissues and in discriminating between stochastic and deterministic processes. Rather than the traditional bastions of EMT, such as development, cancer, fibrosis, wound healing, etc., the TEMTIA-VII session themes were based on concepts such as plasticity, stemness and self-renewal, signalling networks and transcription factors, and systems biology.
