Publisher's Synopsis
The 12th annual Workshop on Eosinophils in Allergy and Related Diseases was held in Tokyo in 1999. Fifteen reports were selected for this volume of proceedings. These were mostly basic studies, such as investigations of the mechanism of eosinophil activation, or the biological importance of cytokines, chemokines, and chemoattractants. It is generally accepted that mediators released by eosinophils are important in the development of chronic allergic inflammation in the upper and lower airways characterized by late asthmatic and nasal reactions, remodelling of bronchial mucosa, and irreversible pathological changes of nasal tissue, although relatively little is known about the mechanism of eosinophil mediator release.