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Electroporation and Electrofusion in Cell Biology

Electroporation and Electrofusion in Cell Biology

1989

Hardback (31 May 1989)

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Publisher's Synopsis

Cells can be funny. Try to grow them with a slightly wrong recipe, and they turn over and die. But hit them with an electric field strong enough to knock over a horse, and they do enough things to justify international meetings, to fill a sizable book, and to lead one to speak of an entirely new technology for cell manipulation. The very improbability of these events not only raises questions about why things happen but also leads to a long list of practical systems in which the application of strong electric fields might enable the merger of cell contents or the introduction of alien but vital material. Inevitably, the basic questions and the practical applications will not keep in step. The questions are intrinsically tough. It is hard enough to analyze the action of the relatively weak fields that rotate or align cells, but it is nearly impossible to predict responses to the cell-shredding bursts of electricity that cause them to fuse or to open up to very large molecular assemblies. Even so, theoretical studies and systematic examination of model systems have produced some creditable results, ideas which should ultimately provide hints of what to try next.

Book information

ISBN: 9780306430435
Publisher: Springer US
Imprint: Springer
Pub date:
Edition: 1989
DEWEY: 574.87
DEWEY edition: 18
Language: English
Number of pages: 436
Weight: 840g
Height: 235mm
Width: 155mm
Spine width: 26mm