Publisher's Synopsis
The mechanisms by which mineral dusts cause cell damage and altered proliferation and/or differentiation of cells are presented in "state-of-the-art" reviews of clinical and basic research. Sessions-in-depth include: Physicochemical properties of dusts as related to their pathogenic potential; molecular biology and oncogenes; growth factors and mechanisms of proliferation; mechanisms of inflammation; involvement of active oxygen species, etc. This comprehensive treatment shows how fibers and particulates cause cell damage, inflammation and disturbancies in growth, and allows us to understand the mechanisms of dust-induced lung disease.
