Publisher's Synopsis
This volume discusses the molecular basis for age-dependent changes in DHEA levels with the aim of determining the potential value of DHEA as a diagnostic and therapeutic tool in age-related disorders. It provides an overview of the biosynthesis and metabolic physiology of DHEA as well as of its biochemical modes of action and possible roles in the immunologic senescence and atherogenesis that are associated with aging. This book significantly furthers the understanding of the physiological role of DHEA throughout the aging process.