Publisher's Synopsis
An overview of new technologies in drug discovery, research and development, this book focuses on the medicinal chemistry and biochemical pharmacology aspects, giving a balanced presentation of drug design, delivery and medicinal testing.;Beginning with an assessment of the status of qualitative and quantitative molecular modelling and structure activity relationships, an appraisal of the use and methodology of X-ray crystallography and nuclear magnetic spectroscopy follows. Site-specific targeting of drugs and the special challenges of peptides and peptidomimetics leads into a discussion on biochemistry (including ligand-binding site methodologies, second messenger systems and ion channels). The final part of the book looks at molecular biology and pharmacology aspects.
