Publisher's Synopsis
The clinical measurement of the therapeutic and adverse effects of a drug plays an important part in drug evaluation and registration.;This book presents full coverage of the principles and practice of the measurement of drug effects in humans and its role in the evaluation and development of new drugs. Clinical interpretation and relevance of data are emphasized as well as the acceptability and accuracy of methodology. Cardiovascular measurement in drug development as well as the assessment of drug effects on the central nervous system are both highlighted.;With contributions from an international, leading team of scientists and clinicians from both academia and industry the book presents the latest information on this essential part of drug development.