Publisher's Synopsis
This book is about the effects of white cells, long considered passive passenger cells, on the quality and safety of cellular blood products. Advances in technology, particularly filtration, have achieved great success in the selective removal of these white cells. Improved safety may manifest as the attenuation of febrile reactions and reduction in sensitization to HLA antigens, viral disease transmission, transfusion-associated immunomodulation, transfusion-related lung injury, and reperfusion injury. All the above aspects of white cell-depleted products as well as a cost/benefit analysis are discussed by acknowledged experts. This book is a state-of-the-art description of the current status of leukodepleted blood products.
