Publisher's Synopsis
This international forum, sponsored by the Nobel Foundation, focussed exclusively on cholinergic mechanisms and was inspired by the first meeting of its kind, organized by Professor Edith Heilbronn and her associates some 20 years ago. The Symposium `Cholinergic Neurotransmission: Functional and Clinical Aspects' took place on the Lidingo Island, Stockholm, in August 1989 and the resulting volume encompasses the contributions of a number of invited scientists prominent in the field of cholinergic neuroscience. The main objective was to provide a detailed overview of the cholinergic research-front of today with emphasis on the basic principles indicating the way to clinical applications. The chapters are organized in such a way as to guide the reader from molecular biology through basic cholinergic pharmacology into clinically oriented contributions that bear upon the number of diseases in which altered cholinergic function is pathophysiologically important, e.g. myasthenia gravis and myasthenic syndromes, disorders of movement and dementia as well as cholinergic mechanisms involved in the regulation of pain, mood and sleep.
