Publisher's Synopsis
This work contains contributions dedicated to intracellular mechanisms leading to cholestasis. Less importance is placed upon the structural damage to bile ductules, and increasing importance is attributed to the plasma membrane in order to explain altered uptake and secretion of bile salts. Several new techniques provide support for both old and new theories, especially in experimental models.;The book will be of great value to doctors of medicine, specifically hepatologists, contributing to the understanding of mechanisms and the prevention of several cholestatic syndromes, and thereby promoting enthusiasms and research in this important field of liver disease.