Publisher's Synopsis
Nineteen papers provide an interdisciplinary perspective on the importance of organic synthesis for contemporary molecular biology. The papers cover such topics as the synthesis of nucleic acids that cannot be amplified by molecular cloning and their use in studying processes of mutagenesis/carcinogenesis and DNA-protein interaction, DNA synthesis and genetic diagnosis, protein design, chemical peptide synthesis in the development of vaccines, and cell-surface oligosaccharides and cell-cell interactions. Solutions to other synthetic problems that cannot be solved by genetic engineering are also presented.
