Publisher's Synopsis
This text draws together the rapidly evolving, diverse, and multidisciplinary subject of capillary electrophoresis (CE). It is designed as a practical guide to be used by a wide audience, including those new to CE as well as more experienced users. This volume presents the capabilities, limitations, potentials, and future challenges facing each area of CE. Key aspects of this technique, such as high resolution capability, full automation, high speed separations, quantification of nanoliter sample volumes, and simultaneous multiple detection capabilities are presented in a concise and logical fashion.;This book is designed to help you make the most of your CE separations, and includes comprehensive information on: electroendo-osmosis, separation efficiency, and joule heating; detection methods; the five major models of CE, with their respective separation principles and advantages. The CE analogs of: sieving-gel electrophoresis and isoelectric focusing; free solution CE, micellar electrokinetic capillary chromatography; entangled polymer matrix-based separation; the application of CE to peptide, protein, and small molecule analysis, supplemented with extensive "hands-on" illustrations.