Publisher's Synopsis
This work describes the remarkable developments in the detection of inherited or acquired genetic mutations. Focusing on the advances in DNA technology, the book examines new methods for large-scale genome mapping, DNA sequencing and protein structure analysis. The progress of molecular diagnostics in revealing significant human disease genes and in understanding;DNA damage and repair is also discussed in the state-of-the-art work. Significant discussions underscore the pervasive and powerful influence of the polymerase chain reaction in all areas of DNA manipulation and analysis.