Publisher's Synopsis
This volume contains practical information and advice for anyone wishing to obtain electron micrographs showing the most accurate ultrastructural detail in thin sections of any type of biological specimen.;The guidelines for the choice of preparative methods are based on an extensive survey of current laboratory practice. The molecular events occurring during fixation and embedding are analyzed in detail. The reason for choosing particular specimen preparation methods are explained and guidance is given on how to modify established techniques to suit individual requirements. All the practical methods advocated are clearly described, with accompanying tables and the results obtainable are illustrated with many electron micrographs.