Publisher's Synopsis
This volume addresses a number of key issues concerning receptor function and control. Special attention is paid to the physiological relevance of information obtained from recombinant receptor-transducer systems, especially in terms of constitutive receptor activity and receptor-transducer pleiotropism. The book also covers genetic basis of disease diagnosis and treatment, the molecular basis of drug-and-receptor trafficking, the importance of receptor-receptor interactions in cell conditioning and the utility of mutagenesis studies and transgenics in drug discovery. This volume should provide insights into novel approaches to serotonin receptor-targeted therapeutics.
