Publisher's Synopsis
This volume integrates information ranging from molecular biology to the use of bone marrow transplants in the treatment of acute lymphoblastic leukemia (ALL). Focusing on controversial issues, this volume unites basic research and clinical data in evaluating recent progress and pointing out areas for future investigations in leukemia diagnosis and therapy. Timely studies of oncogenes, retroviruses and chromosome alterations provide important data on the mechanistic and developmental aspects of;ALL, in addition to exploring the role of hematopoietic growth factors and lymphokines in cell growth regulation. The volume reviews the development of in vitro assays for the analysis of leukemia cells and recent progress in the treatment of adults and children with ALL.
